feat(aia): Protocol Agent MVP complete with one-click generation and Word export

- Add one-click research protocol generation with streaming output

- Implement Word document export via Pandoc integration

- Add dynamic dual-panel layout with resizable split pane

- Implement collapsible content for StatePanel stages

- Add conversation history management with title auto-update

- Fix scroll behavior, markdown rendering, and UI layout issues

- Simplify conversation creation logic for reliability

backend/src/modules/agent/protocol/services/ProtocolContextService.ts

@@ -189,6 +189,36 @@ export class ProtocolContextService {
     return requiredStages.every(stage => context.completedStages.includes(stage));
   }
 
+  /**
+   * 检查是否可以生成研究方案（4/5 必填项）
+   * 必填：科学问题、PICO、研究设计、观察指标
+   * 可选：样本量
+   */
+  canGenerateProtocol(context: ProtocolContextData): boolean {
+    const requiredStages: ProtocolStageCode[] = [
+      'scientific_question',
+      'pico',
+      'study_design',
+      'endpoints',
+    ];
+
+    return requiredStages.every(stage => context.completedStages.includes(stage));
+  }
+
+  /**
+   * 获取缺失的必填阶段
+   */
+  getMissingRequiredStages(context: ProtocolContextData): ProtocolStageCode[] {
+    const requiredStages: ProtocolStageCode[] = [
+      'scientific_question',
+      'pico',
+      'study_design',
+      'endpoints',
+    ];
+
+    return requiredStages.filter(stage => !context.completedStages.includes(stage));
+  }
+
   /**
    * 获取进度百分比
    */